The Ki-67 (Proliferation Marker) Antibody, Cy5.5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to MKI67. This antibody recognizes Human, Mouse, Rat, Goat, and Rabbit antigen. The Ki-67 (Proliferation Marker) Antibody, Cy5.5 Conjugated has been validated for the following applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation